The Restylane family of products includes Restylane,
Restylane-L, Perlane, and Perlane-L. These products
can be used to add volume and fullness to the skin to correct moderate to severe
facial wrinkles and folds, such as the lines from your nose to the corners of
your mouth (nasolabial folds). Restylane may also be used for lip
enhancement in patients over 21 years. Ask your doctor which is right for you.

Important Safety Considerations for the Restylane
family of products

Products in the Restylane family should not be used by people with
previous bad allergies, particularly to microorganisms known as gram-positive
bacteria, or by people with serious allergies to drugs that have previously
required in-hospital treatment. These products should not be used by people with
bleeding disorders. Products should not be injected anywhere except the skin,
just under the skin (Perlane and Perlane-L only), or in the
lips (Restylane only). Restylane-L and Perlane-L
should not be used by anyone with a known allergy to lidocaine.

Use at the site of skin sores, pimples, rashes, hives, cysts, or infection
should be postponed until healing is complete. In these instances, product use
could delay healing or make your skin problems worse. After treatment, you might
have some swelling, redness, pain, bruising, or tenderness. These are typically
mild in severity and normally last less than 7 days in nasolabial folds and less
than 14 days in lips. Swelling may be more likely in patients under 36 years,
and bruising may be more likely in patients over 35 years. Rarely, the doctor
may inject into a blood vessel, which can damage the skin. Although rare, red or
swollen small bumps may occur. If you have had facial cold sores before, an
injection can cause an outbreak. To avoid bruising and bleeding, you should not
use the products if you have recently used drugs that thin your blood or prevent
clotting. Products should not be used during pregnancy, when breastfeeding, or
in patients under 18 years for nasolabial folds.

Treatment volume should be limited to 6.0 mL in wrinkles and folds, such as
nasolabial folds, and limited to 1.5 mL per lip (Restylane only), as
greater amounts significantly increase moderate and severe injection site
reactions. The safety or effectiveness of treatment in areas other than
nasolabial folds and lips (Restylane only) has not been established in
controlled clinical studies.

The Restylane family of products is available in our clinic.


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